KCNN3 and NAPB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNN3	NAPB
Description		potassium calcium-activated channel subfamily N member 3	NSF attachment protein beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body	Vacuolar Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Inward Rectifier Potassium Channel Activity Calmodulin Binding Small Conductance Calcium-activated Potassium Channel Activity	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Ion Transport Potassium Ion Transmembrane Transport	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Synaptic Transmission, Glutamatergic SNARE Complex Disassembly
Pathways		Ca2+ activated K+ channels	COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs		Procaine Miconazole Trimebutine
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Atrial fibrillation ( 28416818 29290336 30061737 29892015 20173747 22544366) Bipolar disorder ( 31043756) Birth weight ( 31043758) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 28552196) Incident atrial fibrillation ( 28416818) Interleukin-6 levels ( 33517400) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Prevalent atrial fibrillation ( 28416818) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Factor VII activity ( 30642921)
Interacting Genes		12 interacting genes: APP CALM1 CLCN7 CRABP2 EMD ERMP1 FCER1G HAX1 ILF2 NAPB SLC27A3 UBAP2L	31 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139
Entrez ID		3782	63908
HPRD ID		04283	17627
Ensembl ID		ENSG00000143603	ENSG00000125814
Uniprot IDs		A0A087WYJ0 Q9UGI6	A0A087WZQ7 Q9H115
PDB IDs
Enriched GO Terms of Interacting Partners?
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