ENTPD8 and CLEC2D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ENTPD8	CLEC2D
Description		ectonucleoside triphosphate diphosphohydrolase 8	C-type lectin domain family 2 member D
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Guanosine-diphosphatase Activity ATP Binding Nucleoside-diphosphatase Activity Nucleoside-triphosphatase Activity Uridine-diphosphatase Activity Metal Ion Binding DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity	Transmembrane Signaling Receptor Activity Carbohydrate Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Nucleoside Monophosphate Biosynthetic Process Nucleoside Diphosphate Biosynthetic Process Nucleoside Diphosphate Catabolic Process	Cell Surface Receptor Signaling Pathway
Pathways		Phosphate bond hydrolysis by NTPDase proteins	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Autoimmune thyroid disease ( 32581359) HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Multiple sclerosis ( 31604244)
Interacting Genes		1 interacting genes: CLEC2D	33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4
Entrez ID		377841	29121
HPRD ID		16864	16134
Ensembl ID		ENSG00000188833	ENSG00000069493
Uniprot IDs		Q5MY95	Q9UHP7 W8JXM2
PDB IDs			4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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