CLEC2D and TMEM80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC2D	TMEM80
Description		C-type lectin domain family 2 member D	transmembrane protein 80
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Integral Component Of Membrane Ciliary Transition Zone
	Molecular Function	Transmembrane Signaling Receptor Activity Carbohydrate Binding Natural Killer Cell Lectin-like Receptor Binding	Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway	Non-motile Cilium Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Multiple sclerosis ( 31604244)
Interacting Genes		33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		29121	283232
HPRD ID		16134	14143
Ensembl ID		ENSG00000069493	ENSG00000177042
Uniprot IDs		Q9UHP7 W8JXM2	A0A0A0MTU4 B7Z7W9 Q96HE8
PDB IDs		4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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