USP17L2 and ELK1

Number of citations of the paper that reports this interaction (PubMedID 30854565)
9

Data Source:
BioGRID (pull down)

		USP17L2	ELK1
Description		ubiquitin specific peptidase 17 like family member 2	ETS transcription factor ELK1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Cytosol	Chromatin Nucleus Nucleoplasm Mitochondrion Dendrite Neuronal Cell Body Axon Terminus
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MAPK Cascade Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Negative Regulation Of Protein Processing Protein Deubiquitination Regulation Of Cell Migration Negative Regulation Of Histone Deacetylation Negative Regulation Of GTPase Activity Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Regulation Of Defense Response To Virus By Host Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination CAAX-box Protein Processing Negative Regulation Of Protein Targeting To Membrane Regulation Of G2/MI Transition Of Meiotic Cell Cycle Regulation Of Ruffle Assembly Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway	Liver Development Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Gene Expression Cell Differentiation Lung Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Testosterone Stimulus Cellular Response To Gamma Radiation Response To Fibroblast Growth Factor Positive Regulation Of Neuron Death
Pathways		Ub-specific processing proteases RAS processing	ERK/MAPK targets NGF-stimulated transcription HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: BRD4 CDK4 CDK6 ELK1 KMT5A LGMN LINC02487 SNAI1 UBC	43 interacting genes: AKAP8 APP BRCA1 CDK6 CEBPB CREBBP CRK EMX1 EP300 EWSR1 FBXO25 FLI1 FOS GRB10 GRB2 HDAC1 HOXB13 ID1 ID2 ID3 KDM6A KLF4 MAD2L2 MAP2K1 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MOB4 NFE2L2 PIAS2 PLCG2 SNCA SRF STARD3NL STK16 TAOK2 UBE2I USP17L2
Entrez ID		377630	2002
HPRD ID		16844	02407
Ensembl ID		ENSG00000223443	ENSG00000126767
Uniprot IDs		Q6R6M4	A0A024R1A7 P19419 Q86SR6
PDB IDs			1DUX 5VVT
Enriched GO Terms of Interacting Partners?
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