ELK1 and USP17L2

Number of citations of the paper that reports this interaction (PubMedID 30854565)
9

Data Source:
BioGRID (pull down)

		ELK1	USP17L2
Description		ETS transcription factor ELK1	ubiquitin specific peptidase 17 like family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Dendrite Neuronal Cell Body Axon Terminus	Nucleus Endoplasmic Reticulum Membrane Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Liver Development Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Gene Expression Cell Differentiation Lung Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Testosterone Stimulus Cellular Response To Gamma Radiation Response To Fibroblast Growth Factor Positive Regulation Of Neuron Death	MAPK Cascade Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Negative Regulation Of Protein Processing Protein Deubiquitination Regulation Of Cell Migration Negative Regulation Of Histone Deacetylation Negative Regulation Of GTPase Activity Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Regulation Of Defense Response To Virus By Host Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination CAAX-box Protein Processing Negative Regulation Of Protein Targeting To Membrane Regulation Of G2/MI Transition Of Meiotic Cell Cycle Regulation Of Ruffle Assembly Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways		ERK/MAPK targets NGF-stimulated transcription HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Ub-specific processing proteases RAS processing
Drugs
Diseases
GWAS
Interacting Genes		43 interacting genes: AKAP8 APP BRCA1 CDK6 CEBPB CREBBP CRK EMX1 EP300 EWSR1 FBXO25 FLI1 FOS GRB10 GRB2 HDAC1 HOXB13 ID1 ID2 ID3 KDM6A KLF4 MAD2L2 MAP2K1 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MOB4 NFE2L2 PIAS2 PLCG2 SNCA SRF STARD3NL STK16 TAOK2 UBE2I USP17L2	9 interacting genes: BRD4 CDK4 CDK6 ELK1 KMT5A LGMN LINC02487 SNAI1 UBC
Entrez ID		2002	377630
HPRD ID		02407	16844
Ensembl ID		ENSG00000126767	ENSG00000223443
Uniprot IDs		A0A024R1A7 P19419 Q86SR6	Q6R6M4
PDB IDs		1DUX 5VVT
Enriched GO Terms of Interacting Partners?
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