MIA3 and SEC16A

Number of citations of the paper that reports this interaction (PubMedID 28442536)
25

Data Source:
BioGRID (pull down)

		MIA3	SEC16A
Description		MIA SH3 domain ER export factor 3	SEC16 homolog A, endoplasmic reticulum export factor
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Cargo Receptor Activity	Protein Binding
	Biological Process	Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Leukocyte Migration Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Endoplasmic Reticulum Organization Negative Regulation Of Cell Adhesion Protein Secretion Protein Transport Negative Regulation Of Cell Migration Vesicle Cargo Loading Wound Healing Lipoprotein Transport Protein Localization To Endoplasmic Reticulum Exit Site COPII-coated Vesicle Cargo Loading Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Endoplasmic Reticulum Organization Golgi Organization Substantia Nigra Development Protein Exit From Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Golgi To Plasma Membrane CFTR Protein Transport Protein Stabilization Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Plasma Membrane
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation	COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 29212778 30104761 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 17634449 21378990) Myocardial infarction ( 33532862 26343387) Myocardial infarction (early onset) ( 19198609)	Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798 32041948) Eosinophil counts ( 27863252) Height ( 28552196) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 32888494) Serum alkaline phosphatase levels ( 33547301) Squamous cell carcinoma ( 31174203) Triglyceride levels ( 32154731) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		16 interacting genes: CACNA1A CEP55 CLIC3 COL7A1 FXR2 HOMER3 HSD17B14 ITGAX LENG8 MTNR1B NCK2 PRDM14 SEC16A SEC23A SEC24C TRIM27	2 interacting genes: MIA3 SEC23A
Entrez ID		375056	9919
HPRD ID		18918	11075
Ensembl ID		ENSG00000154305	ENSG00000148396
Uniprot IDs		Q5JRA6	F1T0I1 O15027
PDB IDs		5KYN 5KYU 5KYW
Enriched GO Terms of Interacting Partners?
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