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MIA3 and COL7A1
Number of citations of the paper that reports this interaction (PubMedID
19269366
)
144
Data Source:
BioGRID
(pull down)
MIA3
COL7A1
Description
MIA SH3 domain ER export factor 3
collagen type VII alpha 1 chain
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Endoplasmic Reticulum Exit Site
Extracellular Region
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
COPII-coated ER To Golgi Transport Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Cargo Receptor Activity
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Biological Process
Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Leukocyte Migration
Exocytosis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endocytosis
Endoplasmic Reticulum Organization
Negative Regulation Of Cell Adhesion
Protein Secretion
Protein Transport
Negative Regulation Of Cell Migration
Vesicle Cargo Loading
Wound Healing
Lipoprotein Transport
Protein Localization To Endoplasmic Reticulum Exit Site
COPII-coated Vesicle Cargo Loading
Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Negative Regulation Of Leukocyte Cell-cell Adhesion
Negative Regulation Of Lymphocyte Migration
Cell Adhesion
Epidermis Development
Negative Regulation Of Endopeptidase Activity
Endodermal Cell Differentiation
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Cargo concentration in the ER
Post-translational protein phosphorylation
Collagen degradation
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
COPII-mediated vesicle transport
Integrin cell surface interactions
Anchoring fibril formation
Laminin interactions
Laminin interactions
Cargo concentration in the ER
Collagen chain trimerization
Drugs
Diseases
GWAS
Coronary artery disease (
32469254
29212778
30104761
26343387
33020668
)
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) (
28714975
)
Coronary heart disease (
17634449
21378990
)
Myocardial infarction (
33532862
26343387
)
Myocardial infarction (early onset) (
19198609
)
Age at first sexual intercourse (
27089180
)
Apolipoprotein A1 levels (
32203549
)
Blood protein levels (
29875488
)
Bone fracture in osteoporosis (
28580392
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
16 interacting genes:
CACNA1A
CEP55
CLIC3
COL7A1
FXR2
HOMER3
HSD17B14
ITGAX
LENG8
MTNR1B
NCK2
PRDM14
SEC16A
SEC23A
SEC24C
TRIM27
16 interacting genes:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MIA3
MMP2
NPHP3
SHKBP1
THBS1
ZC3H7A
Entrez ID
375056
1294
HPRD ID
18918
00358
Ensembl ID
ENSG00000154305
ENSG00000114270
Uniprot IDs
Q5JRA6
Q02388
Q59F16
PDB IDs
5KYN
5KYU
5KYW
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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