HiPPIP
Home
About
SZ Genes
People
Help
Advanced Search
JUN and SOX10
Number of citations of the paper that reports this interaction (PubMedID
16582099
)
62
Data Source:
HPRD
(in vitro)
JUN
SOX10
Description
Jun proto-oncogene, AP-1 transcription factor subunit
SRY-box transcription factor 10
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromosome
Chromatin
Euchromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytosol
Plasma Membrane
Transcription Factor AP-1 Complex
Chromatin
Nucleus
Nucleoplasm
Extrinsic Component Of Mitochondrial Outer Membrane
Molecular Function
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
RNA Binding
GTPase Activator Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
CAMP Response Element Binding
Identical Protein Binding
Ubiquitin-like Protein Ligase Binding
Protein-containing Complex Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
R-SMAD Binding
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
DNA-binding Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Release Of Cytochrome C From Mitochondria
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Signaling Pathway
Ras Protein Signal Transduction
Aging
Learning
Circadian Rhythm
Response To Radiation
Response To Xenobiotic Stimulus
Response To Mechanical Stimulus
Response To Lipopolysaccharide
Response To Cytokine
Cellular Response To Reactive Oxygen Species
Regulation Of Cell Population Proliferation
Response To Hydrogen Peroxide
Positive Regulation Of Apoptotic Process
Negative Regulation Of DNA Binding
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation By Host Of Viral Transcription
Positive Regulation By Host Of Viral Transcription
Positive Regulation Of Monocyte Differentiation
Positive Regulation Of DNA Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Catalytic Activity
Cellular Response To Potassium Ion Starvation
Response To CAMP
Regulation Of Cell Cycle
Membrane Depolarization
SMAD Protein Signal Transduction
Cellular Response To Cadmium Ion
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Positive Regulation Of DNA-templated Transcription, Initiation
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Neural Crest Cell Migration
Morphogenesis Of An Epithelium
Positive Regulation Of Neuroblast Proliferation
Regulation Of Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Peripheral Nervous System Development
Anatomical Structure Morphogenesis
Negative Regulation Of Schwann Cell Proliferation
Positive Regulation Of Gene Expression
Oligodendrocyte Development
Positive Regulation Of Gliogenesis
Central Nervous System Myelination
Melanocyte Differentiation
Positive Regulation Of Myelination
Lacrimal Gland Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Enteric Nervous System Development
Digestive Tract Morphogenesis
Developmental Growth
Oligodendrocyte Differentiation
Morphogenesis Of A Branching Epithelium
Cellular Response To Progesterone Stimulus
Cellular Response To Xenobiotic Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Pre-NOTCH Transcription and Translation
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
FCERI mediated MAPK activation
Activation of the AP-1 family of transcription factors
Activation of anterior HOX genes in hindbrain development during early embryogenesis
MAPK6/MAPK4 signaling
TP53 Regulates Transcription of DNA Repair Genes
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
WNT5:FZD7-mediated leishmania damping
EGR2 and SOX10-mediated initiation of Schwann cell myelination
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Adapalene
Vinblastine
Pseudoephedrine
Irbesartan
Arsenic trioxide
LGD-1550
Diseases
GWAS
Aspartate aminotransferase levels (
33547301
)
Cognitive performance (
19734545
)
Night sleep phenotypes (
27126917
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
189 interacting genes:
ABL1
AKAP5
APLP2
APP
AR
ARRB1
ATF1
ATF2
ATF3
ATF4
BATF
BATF2
BBS7
BCL3
BCL6
BLM
BRCA1
CASP9
CCND1
CEBPE
CEBPG
CLINT1
COP1
COPS5
CREB3
CREB5
CREBBP
CSNK2A1
DAB1
DACH1
DDIT3
DDX21
DHX9
DNMT3L
EDF1
EGR1
ELF3
ELOF1
EN1
EP300
EPAS1
ERG
ESR1
ETS1
ETS2
ETV1
ETV4
EWSR1
FBXW7
FOS
FOSB
FOSL1
FOSL2
GART
GATA2
GOPC
GPR18
GSK3B
GTF2B
GTF2E2
GTF2F1
GTF2F2
HCFC1
HDAC3
HDAC9
HDGF
HHEX
HIF1A
HMGA1
HNRNPM
HOXA9
HOXC8
HSP90AA1
HSPA8
IKBKB
IRAK1
ISCU
ITCH
ITPK1
JDP2
KLF5
KMT2C
KPNA2
M6PR
MACF1
MAF
MAFB
MAP2K4
MAP2K7
MAPK1
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MAPRE3
MBD3
MDM2
MOK
MTA1
MYBBP1A
MYOD1
NACA
NAT14
NCOA1
NCOA2
NCOA3
NCOA6
NCOR2
NEDD4
NELFB
NFE2L1
NFE2L2
NFYA
NFYC
NR3C1
NR5A1
NRIP1
NTRK3
PACS1
PHOX2A
PIAS1
PIAS2
PIN1
PML
POU1F1
PPARG
PPP3CB
PPP4C
PRKD1
PRKDC
PRRC2A
RB1
RBM39
RELA
RNF187
ROR1
RPL18A
RPS6KA2
RUNX1
RUNX2
SKI
SMAD2
SMAD3
SMAD4
SMARCD1
SMARCD3
SNAPC5
SNIP1
SNRK
SOX10
SOX8
SP1
SPI1
SPIB
STAT1
STAT3
STAT4
STRN4
SUMO1
SUMO2
SUMO3
SUMO4
TACSTD2
TAF1
TAF4
TBP
TCF20
TCF4
TDG
TGIF1
TOP1
TOP2A
TP53
TPM1
TPM2
TRAF2
TRIP4
TSC22D3
TSG101
UBB
UBC
UBE2I
USP6
VAV1
VDR
ZBTB7C
36 interacting genes:
ALX4
C10orf55
CDK6
CEBPA
CRX
DAZAP2
DLX5
EGR2
EXOC5
GSK3B
HHEX
HIVEP1
HOXA3
HOXC4
HSF4
JUN
MAGED1
MAPK1
MEOX1
NMI
OLIG2
PAX3
PAX6
POU3F2
POU3F3
POU5F1
POU6F2
PRRX1
PRRX2
SP1
SUMO1
SUMO2
SUMO3
TCF12
UBE2I
UTF1
Entrez ID
3725
6663
HPRD ID
01302
03752
Ensembl ID
ENSG00000177606
ENSG00000100146
Uniprot IDs
P05412
A0A024R1N6
P56693
PDB IDs
1A02
1FOS
1JNM
1JUN
1S9K
1T2K
5FV8
5T01
6Y3V
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?