INHBB and TDGF1

Number of citations of the paper that reports this interaction (PubMedID 28126904)
3

Data Source:
BioGRID (pull down)

		INHBB	TDGF1
Description		inhibin subunit beta B	teratocarcinoma-derived growth factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm Cell Periphery	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Extrinsic Component Of Plasma Membrane Anchored Component Of Membrane Membrane Raft
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity Host Cell Surface Receptor Binding	Signaling Receptor Binding Protein Binding Growth Factor Activity Nodal Binding Activin Receptor Binding
	Biological Process	Ovarian Follicle Development Defense Response Cellular Response To Starvation Response To Wounding Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Negative Regulation Of Hepatocyte Growth Factor Production Cellular Response To Insulin Stimulus Activin Receptor Signaling Pathway Cellular Response To Leptin Stimulus Adhesion Of Symbiont To Host Cell Fat Cell Differentiation Negative Regulation Of Insulin Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Oocyte Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway	Blood Vessel Development Morphogenesis Of A Branching Structure Cell Migration Involved In Sprouting Angiogenesis Epidermal Growth Factor Receptor Signaling Pathway Determination Of Left/right Symmetry Heart Development Positive Regulation Of Cell Population Proliferation Anterior/posterior Axis Specification, Embryo Embryo Development Ending In Birth Or Egg Hatching Anterior/posterior Pattern Specification Regulation Of Signal Transduction Positive Regulation Of Endothelial Cell Migration Peptidyl-serine Phosphorylation Cell Differentiation Positive Regulation Of Cell Migration Mammary Gland Development Cellular Response To Hepatocyte Growth Factor Stimulus Nodal Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Anatomical Structure Development Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Interferon-gamma Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus
Pathways		Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin	Signaling by NODAL Regulation of signaling by NODAL POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23326517) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Breast size ( 22747683 27182965) Obesity ( 21552555) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 31985003 23263486)	Blood protein levels ( 29875488 28240269) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B BMPR2 FNTA IGSF1 INHA INHBA INHBC TDGF1	22 interacting genes: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ANG AP2S1 BAG6 BMP4 BMP6 BMP7 BMPR1A BMPR2 COPS6 FARSA FBLN1 GDF3 GDF9 INHBB LRIF1 NODAL TGFBR2
Entrez ID		3625	6997
HPRD ID		00934	01757
Ensembl ID		ENSG00000163083	ENSG00000241186
Uniprot IDs		P09529	F5H1T8 P13385
PDB IDs
Enriched GO Terms of Interacting Partners?
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