INHBB and INHBC

Number of citations of the paper that reports this interaction (PubMedID 11134153)
17

Data Source:
HPRD (in vitro)

		INHBB	INHBC
Description		inhibin subunit beta B	inhibin subunit beta C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm Cell Periphery	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity Host Cell Surface Receptor Binding	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Growth Factor Activity
	Biological Process	Ovarian Follicle Development Defense Response Cellular Response To Starvation Response To Wounding Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Negative Regulation Of Hepatocyte Growth Factor Production Cellular Response To Insulin Stimulus Activin Receptor Signaling Pathway Cellular Response To Leptin Stimulus Adhesion Of Symbiont To Host Cell Fat Cell Differentiation Negative Regulation Of Insulin Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Oocyte Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction
Pathways		Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin	Glycoprotein hormones
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23326517) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Breast size ( 22747683 27182965) Obesity ( 21552555) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 31985003 23263486)	Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Asthma ( 31619474) Blood protein levels ( 30072576) Body mass index and HDL-C (pairwise) ( 33619380) Body mass index and triglycerides (pairwise) ( 33619380) Chronic kidney disease ( 29124443) Chronotype ( 30696823) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting glucose ( 34059833) Glomerular filtration rate (creatinine) ( 26831199) Gout ( 33832965) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hemoglobin levels ( 32327693) Serum uric acid levels ( 30993211) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787)
Interacting Genes		12 interacting genes: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B BMPR2 FNTA IGSF1 INHA INHBA INHBC TDGF1	6 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B INHBA INHBB
Entrez ID		3625	3626
HPRD ID		00934	03136
Ensembl ID		ENSG00000163083	ENSG00000175189
Uniprot IDs		P09529	P55103
PDB IDs
Enriched GO Terms of Interacting Partners?
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