IMPDH1 and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IMPDH1	RAD54L2
Description		inosine monophosphate dehydrogenase 1	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Secretory Granule Lumen Azurophil Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Metal Ion Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process	DNA Duplex Unwinding
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine 6-Chloropurine Riboside, 5'-Monophosphate VX-148 Taribavirin
Diseases
GWAS		Pelvic organ prolapse ( 32184442)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		8 interacting genes: DDIT4L GMNN HTRA1 OGT PIAS2 RAD54L2 RNF4 UBE2I	42 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 IMPDH2 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		3614	23132
HPRD ID		08853	10018
Ensembl ID		ENSG00000106348	ENSG00000164080
Uniprot IDs		B3KRZ3 P20839 Q6ZNB1	B3KV54 Q9Y4B4
PDB IDs		1JCN
Enriched GO Terms of Interacting Partners?
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