RAD54L2 and IMPDH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RAD54L2	IMPDH1
Description		RAD54 like 2	inosine monophosphate dehydrogenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Nucleus Cytoplasm Cytosol Secretory Granule Lumen Azurophil Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Metal Ion Binding
	Biological Process	DNA Duplex Unwinding	GMP Biosynthetic Process GTP Biosynthetic Process
Pathways			Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs			NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine 6-Chloropurine Riboside, 5'-Monophosphate VX-148 Taribavirin
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163)	Pelvic organ prolapse ( 32184442)
Interacting Genes		42 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 IMPDH2 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A	8 interacting genes: DDIT4L GMNN HTRA1 OGT PIAS2 RAD54L2 RNF4 UBE2I
Entrez ID		23132	3614
HPRD ID		10018	08853
Ensembl ID		ENSG00000164080	ENSG00000106348
Uniprot IDs		B3KV54 Q9Y4B4	B3KRZ3 P20839 Q6ZNB1
PDB IDs			1JCN
Enriched GO Terms of Interacting Partners?
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