IGHMBP2 and LSM8

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		IGHMBP2	LSM8
Description		immunoglobulin mu DNA binding protein 2	LSM8 homolog, U6 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Body Axon Growth Cone Ribonucleoprotein Complex	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	TRNA Binding DNA Binding DNA Helicase Activity Single-stranded DNA Binding RNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Transcription Factor Binding ATP-dependent Activity, Acting On RNA Zinc Ion Binding ATP Hydrolysis Activity 5'-3' RNA Helicase Activity Identical Protein Binding Ribosome Binding 5'-3' DNA Helicase Activity	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	DNA Replication DNA Repair DNA Recombination Translation DNA Duplex Unwinding	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Heel bone mineral density ( 28869591)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 33627673 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 33082346) Smoking status (current vs never) ( 33082346) Triglyceride levels ( 30108155)
Interacting Genes		1 interacting genes: LSM8	49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		3508	51691
HPRD ID		02736	06288
Ensembl ID		ENSG00000132740	ENSG00000128534
Uniprot IDs		P38935	A4D0W0 O95777
PDB IDs		1MSZ 2LRR 4B3F 4B3G	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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