LSM8 and THUMPD3

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LSM8	THUMPD3
Description		LSM8 homolog, U6 small nuclear RNA associated	THUMP domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex	Nucleolus Cytosol
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	RNA Binding Protein Binding TRNA (guanine) Methyltransferase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	TRNA Methylation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 33627673 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 33082346) Smoking status (current vs never) ( 33082346) Triglyceride levels ( 30108155)
Interacting Genes		49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	2 interacting genes: LSM8 TRMT112
Entrez ID		51691	25917
HPRD ID		06288	15507
Ensembl ID		ENSG00000128534	ENSG00000134077
Uniprot IDs		A4D0W0 O95777	A0A024R2D3 Q9BV44
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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