IGFBP6 and CDIPT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IGFBP6	CDIPT
Description		insulin like growth factor binding protein 6	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Insulin-like Growth Factor Binary Complex	Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Fibronectin Binding Signaling Receptor Binding Protein Binding Insulin-like Growth Factor I Binding Insulin-like Growth Factor II Binding Identical Protein Binding	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAPK Cascade Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway	Phosphatidylinositol Biosynthetic Process CDP-diacylglycerol Metabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	Synthesis of PI
Drugs			scyllo-inositol
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)	Mean platelet volume ( 27863252)
Interacting Genes		40 interacting genes: ALPP ANKRD11 AQP1 C1orf74 CCDC116 CCDC28A CDIPT CREB5 DDX10 EFEMP1 EFEMP2 ENKD1 EPDR1 ERBB3 GAS8 GET3 IGF1 IGF2 KRTAP10-8 KRTAP5-7 KRTAP5-9 MBD3 MEIS2 MSGN1 MYCBP2 NCALD PLEKHA7 POU4F2 RABGGTB RANBP10 SDCBP SGTA SMCP TF UBAC1 UBQLN1 UBQLN2 UBQLN4 ZNF417 ZNF587	57 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BCKDK BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SDCBP SIGLEC12 SLC10A6 SLC16A7 SLC7A1 TLCD4 TMX2 UNC93A VMA21
Entrez ID		3489	10423
HPRD ID		00902	12063
Ensembl ID		ENSG00000167779	ENSG00000103502
Uniprot IDs		P24592	A8K3L7 B3KY94 O14735
PDB IDs		1RMJ
Enriched GO Terms of Interacting Partners?
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