CDIPT and SIGLEC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDIPT	SIGLEC12
Description		CDP-diacylglycerol--inositol 3-phosphatidyltransferase	sialic acid binding Ig like lectin 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process CDP-diacylglycerol Metabolic Process	Cell Adhesion
Pathways		Synthesis of PI	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		scyllo-inositol
Diseases
GWAS		Mean platelet volume ( 27863252)	Blood protein levels ( 29875488)
Interacting Genes		57 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BCKDK BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SDCBP SIGLEC12 SLC10A6 SLC16A7 SLC7A1 TLCD4 TMX2 UNC93A VMA21	18 interacting genes: ACSF2 ADIPOQ ATP5PF CDIPT CLEC4G CMAS CTSA DNAAF3 DNAJC30 IL1RL1 MGST1 PLPP6 PLPPR2 PTCH1 PTPN11 PTPN6 TMPRSS4 YIPF1
Entrez ID		10423	89858
HPRD ID		12063	16195
Ensembl ID		ENSG00000103502	ENSG00000254521
Uniprot IDs		A8K3L7 B3KY94 O14735	Q96PQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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