Description |
insulin like growth factor binding protein 3 |
matrix metallopeptidase 3 |
Image |
No pdb structure |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Marimastat
- N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide
- 3-Methylpyridine
- A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor
- N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide
- (1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine
- 3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid
- Hydroxyaminovaline
- 4-methoxybenzenesulfinate
- 5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione
- 1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide
- N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide
- R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid
- 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide
- [4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID
- [2-(5-Mercapto-[1,3,4]thiadiazol-2-ylcarbamoyl)-1-phenyl-ethyl]-carbamic acid benzyl ester
- 2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide
- N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide
- 3-[(4'-cyanobiphenyl-4-yl)oxy]-N-hydroxypropanamide
- N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
- N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID
- 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER
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Diseases |
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GWAS |
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- Alzheimer's disease ( 22832961)
- Blood protein levels ( 30072576 28240269)
- Blood protein levels in cardiovascular risk ( 28369058)
- Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
- Peripheral artery disease ( 31285632)
- Post bronchodilator FEV1/FVC ratio ( 26634245)
- Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
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Interacting Genes |
39 interacting genes:
ADAM12
AURKA
BMPR1A
BUB1
CAV1
CCND1
CD44
COL1A1
CSNK2A1
CTSD
CTSG
CTSL
F2
FBXW7
FN1
GPI
GTF3C1
IGF1
IGF1R
IGF2
IGFALS
KLK3
KLKB1
KPNB1
KRAS
LTBP1
MLH3
MMP1
MMP2
MMP3
PAPPA2
PLG
POLA2
PPARG
RAD54B
RXRA
STK11
TF
WDR5
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19 interacting genes:
ACAN
BCAN
CCL13
CCL2
CCL7
CCL8
DCN
HAPLN1
IGFBP3
MEOX2
MMP14
PLG
SERPINE1
SPOCK1
SPOCK3
SPP1
TIMP1
TIMP3
TNFSF11
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Entrez ID |
3486 |
4314 |
HPRD ID |
00899 |
01703 |
Ensembl ID |
ENSG00000146674
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ENSG00000149968
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Uniprot IDs |
B3KPF0
P17936
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P08254
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PDB IDs |
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1B3D
1B8Y
1BIW
1BM6
1BQO
1C3I
1C8T
1CAQ
1CIZ
1CQR
1D5J
1D7X
1D8F
1D8M
1G05
1G49
1G4K
1HFS
1HY7
1M1W
1OO9
1QIA
1QIC
1SLM
1SLN
1UEA
1UMS
1UMT
1USN
2D1O
2JNP
2JT5
2JT6
2SRT
2USN
3OHL
3OHO
3USN
4DPE
4G9L
4JA1
6MAV
6N9D
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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