SLC10A6 and SLC7A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC10A6	SLC7A1
Description		solute carrier family 10 member 6	solute carrier family 7 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity	L-ornithine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity Arginine Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Sodium-dependent Organic Anion Transport Transmembrane Transport	Amino Acid Transport L-amino Acid Transport Lysine Transport Ornithine Transport Positive Regulation Of T Cell Proliferation Amino Acid Import Across Plasma Membrane L-arginine Import Across Plasma Membrane Transport Across Blood-brain Barrier L-ornithine Transmembrane Transport L-lysine Transmembrane Transport L-histidine Import Across Plasma Membrane Arginine Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Amino acid transport across the plasma membrane
Drugs			L-Lysine Arginine Ornithine
Diseases
GWAS		Eyebrow thickness ( 26926045) Insulin-related traits ( 22791750) Refractive error ( 32231278)	Blood osmolality (transformed sodium) ( 28360221) Diastolic blood pressure ( 27841878) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		146 interacting genes: ACSL5 ANKRD46 APOD ARL6IP1 ARV1 ATP13A1 BMP10 BTN2A2 C11orf24 C2CD2L CCDC167 CCL4 CDIPT CDS1 CLDND2 CMTM5 CNIH1 COL4A5 COMT COX20 CYB5B CYB5R3 CYP4F2 DERL1 DGAT2L6 EMC6 ERG28 FA2H FAM3C FAXDC2 FIS1 FKBP8 FMO1 FUNDC2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP1 GJB6 GLB1 GOLT1B GOSR2 GPR151 GYPA GYPC HTATIP2 IGFBP5 ITGAM LPAR3 LSS MALL MFSD5 MFSD6 MGLL MS4A1 NAT8 NEU1 NINJ2 NRM OR7D4 ORMDL1 OSMR PEDS1-UBE2V1 PEX16 PIP4P1 PIP4P2 PLLP PLP1 PNLIPRP1 PRAF2 PRRT2 PSEN1 PSENEN RNF24 RTP2 RUSF1 SACM1L SCAMP4 SCAMP5 SCD SERP1 SERP2 SFT2D2 SFXN1 SLC12A7 SLC25A46 SLC29A2 SLC30A2 SLC30A3 SLC35C2 SLC35G2 SLC38A1 SLC39A6 SLC39A9 SLC41A1 SLC66A2 SLC7A1 SMAGP SMIM1 SNORC STATH STX12 STX7 STX8 SYNGR1 SYNJ2BP TAP1 TECR TF TM4SF4 TMEM107 TMEM11 TMEM119 TMEM120B TMEM128 TMEM143 TMEM14A TMEM14C TMEM203 TMEM208 TMEM218 TMEM229B TMEM234 TMEM239 TMEM242 TMEM252 TMEM262 TMEM50B TMEM60 TMEM65 TMEM86A TMEM86B TPRG1 TREX1 TSNARE1 TSPAN2 TSPO2 TVP23B UBE2J1 UNC50 VAMP4 YIPF1 YIPF2 YIPF6 ZDHHC15 ZFPL1	57 interacting genes: ADGRB3 APOA2 APP AQP6 ATP6V0C C8A CBLIF CCL4 CCL4L2 CD40 CD79A CDIPT CERS4 CMTM2 COMT CREB3L1 EMC6 FAM241B FATE1 FCER1G GALNT15 GET1 GLB1 GPR152 HERPUD2 LEPROT LEPROTL1 LMNA MFF MGST3 MS4A13 NUCB2 ORMDL3 PDCD1LG2 PNLIPRP1 PSCA PTPN9 RNF144A SACM1L SCN3B SEC23A SLC10A6 SLC18A2 SLC30A2 SLC39A2 SLC39A9 SLC52A1 SMCO4 ST6GAL2 STIM1 TMBIM6 TMEM14A TMEM19 TMEM237 TRARG1 TSPO2 YIPF4
Entrez ID		345274	6541
HPRD ID		11593	00091
Ensembl ID		ENSG00000145283	ENSG00000139514
Uniprot IDs		Q3KNW5	A0A024RDQ9 P30825
PDB IDs
Enriched GO Terms of Interacting Partners?
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