SLC10A6 and MGLL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC10A6	MGLL
Description		solute carrier family 10 member 6	monoglyceride lipase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Extrinsic Component Of Membrane
	Molecular Function	Protein Binding Bile Acid:sodium Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity	Lysophospholipase Activity Protein Binding Lipase Activity Protein Homodimerization Activity Acylglycerol Lipase Activity
	Biological Process	Sodium Ion Transport Bile Acid And Bile Salt Transport Sodium-dependent Organic Anion Transport Transmembrane Transport	Lipid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Arachidonic Acid Metabolic Process Triglyceride Catabolic Process Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway
Pathways		Transport of bile salts and organic acids, metal ions and amine compounds	Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Insulin-related traits ( 22791750) Refractive error ( 32231278)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		146 interacting genes: ACSL5 ANKRD46 APOD ARL6IP1 ARV1 ATP13A1 BMP10 BTN2A2 C11orf24 C2CD2L CCDC167 CCL4 CDIPT CDS1 CLDND2 CMTM5 CNIH1 COL4A5 COMT COX20 CYB5B CYB5R3 CYP4F2 DERL1 DGAT2L6 EMC6 ERG28 FA2H FAM3C FAXDC2 FIS1 FKBP8 FMO1 FUNDC2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP1 GJB6 GLB1 GOLT1B GOSR2 GPR151 GYPA GYPC HTATIP2 IGFBP5 ITGAM LPAR3 LSS MALL MFSD5 MFSD6 MGLL MS4A1 NAT8 NEU1 NINJ2 NRM OR7D4 ORMDL1 OSMR PEDS1-UBE2V1 PEX16 PIP4P1 PIP4P2 PLLP PLP1 PNLIPRP1 PRAF2 PRRT2 PSEN1 PSENEN RNF24 RTP2 RUSF1 SACM1L SCAMP4 SCAMP5 SCD SERP1 SERP2 SFT2D2 SFXN1 SLC12A7 SLC25A46 SLC29A2 SLC30A2 SLC30A3 SLC35C2 SLC35G2 SLC38A1 SLC39A6 SLC39A9 SLC41A1 SLC66A2 SLC7A1 SMAGP SMIM1 SNORC STATH STX12 STX7 STX8 SYNGR1 SYNJ2BP TAP1 TECR TF TM4SF4 TMEM107 TMEM11 TMEM119 TMEM120B TMEM128 TMEM143 TMEM14A TMEM14C TMEM203 TMEM208 TMEM218 TMEM229B TMEM234 TMEM239 TMEM242 TMEM252 TMEM262 TMEM50B TMEM60 TMEM65 TMEM86A TMEM86B TPRG1 TREX1 TSNARE1 TSPAN2 TSPO2 TVP23B UBE2J1 UNC50 VAMP4 YIPF1 YIPF2 YIPF6 ZDHHC15 ZFPL1	26 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MFSD14B MRPS5 MSRB3 PEX12 SDCBP SLC10A6 SLC66A2 SLC7A14 STOM TMEM35A TMX2
Entrez ID		345274	11343
HPRD ID		11593	17574
Ensembl ID		ENSG00000145283	ENSG00000074416
Uniprot IDs		Q3KNW5	A0A0C4DFN3 B2ZGL7 E7EWX8 Q99685
PDB IDs			3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0
Enriched GO Terms of Interacting Partners?
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