RTP2 and GJB5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RTP2	GJB5
Description		receptor transporter protein 2	gap junction protein beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding Olfactory Receptor Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development
Pathways		Olfactory Signaling Pathway	Gap junction assembly
Drugs
Diseases
GWAS		Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)	BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		72 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MFSD5 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SEC11C SGPL1 SLC10A6 SLC14A1 SLC34A2 SLC39A9 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21	45 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B DNALI1 ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1
Entrez ID		344892	2709
HPRD ID		12371	06840
Ensembl ID		ENSG00000198471	ENSG00000189280
Uniprot IDs		Q5QGT7	A0A654IE64 O95377
PDB IDs
Enriched GO Terms of Interacting Partners?
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