GJB5 and APOL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GJB5	APOL2
Description		gap junction protein beta 5	apolipoprotein L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Connexin Complex Integral Component Of Membrane	Extracellular Region Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding
	Biological Process	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development	Lipid Metabolic Process Lipid Transport Acute-phase Response Multicellular Organism Development Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)	Epigenetic age acceleration in alcohol use disorder ( 31466081)
Interacting Genes		45 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B DNALI1 ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1	33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6
Entrez ID		2709	23780
HPRD ID		06840	06263
Ensembl ID		ENSG00000189280	ENSG00000128335
Uniprot IDs		A0A654IE64 O95377	A0A024R1M8 J3KQL8 Q9BQE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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