FAM221A and SUMO3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM221A	SUMO3
Description		family with sequence similarity 221 member A	small ubiquitin like modifier 3
Image		No pdb structure
GO Annotations	Cellular Component		Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body
	Molecular Function	Protein Binding	Protein Binding Protein Tag Ubiquitin-like Protein Ligase Binding
	Biological Process		Protein Sumoylation Negative Regulation Of DNA Binding Regulation Of Protein Localization To Nucleus
Pathways			SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS			Delirium ( 29631748)
Interacting Genes		15 interacting genes: ANKS1A CDPF1 CYSRT1 HOXA1 KRTAP1-1 KRTAP21-2 KRTAP4-11 LHX3 MEOX2 NBPF19 NOTCH2NLA PFDN5 PRRG2 SUMO3 ZNF417	55 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 MORC3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TRAPPC10 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496
Entrez ID		340277	6612
HPRD ID		14706	03754
Ensembl ID		ENSG00000188732	ENSG00000184900
Uniprot IDs		A0A024RA57 A4D161 B8ZZQ8	P55854
PDB IDs			1U4A 2IO1 2MP2 6K5R 6NNQ
Enriched GO Terms of Interacting Partners?
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