HSBP1 and RPL13

		HSBP1	RPL13
Description		heat shock factor binding protein 1	ribosomal protein L13
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton Axon Cytoplasm	Nucleus Nucleolus Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Axonal Transport Of Mitochondrion Endodermal Cell Differentiation Cellular Heat Acclimation	Blastocyst Development Cytoplasmic Translation Translation Bone Development
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Hair morphology traits ( 30166351)
Interacting Genes		25 interacting genes: BLOC1S5 BRK1 CCHCR1 CD1B CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPHOSPH6 MPP7 NOTCH2NLA RPL13 SDCBP SDCBP2 SDR42E1 WASHC1 WASHC3 ZBTB25	23 interacting genes: ANXA7 CDK12 CEP70 CSNK2A1 CSNK2B DAXX DUX4 ERCC6 HSBP1 ILK IPO5 MAP2K3 MAPKAPK5 OGT PTEN RAD21 RELA SMN1 SPP1 SRPK2 TERF2 TK1 UPF2
Entrez ID		3281	6137
HPRD ID		05185	06428
Ensembl ID		ENSG00000230989	ENSG00000167526
Uniprot IDs		O75506	A8K4C8 P26373
PDB IDs		3CI9	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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