HOXC9 and HOXD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXC9	HOXD1
Description		homeobox C9	homeobox D1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis	Regulation Of Transcription By RNA Polymerase II Sensory Perception Of Pain Neuron Differentiation Embryonic Skeletal System Development
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body shape index ( 34021172) Heel bone mineral density ( 30598549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Epithelial ovarian cancer ( 25581431) Estimated glomerular filtration rate ( 31451708) Eye morphology ( 29921221) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Monobrow ( 27182965) Ovarian cancer ( 20852632) Upper eyelid morphology ( 29921221)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	2 interacting genes: DYNC1I2 HOXC9
Entrez ID		3225	3231
HPRD ID		00857	00870
Ensembl ID		ENSG00000180806	ENSG00000128645
Uniprot IDs		A0A024RAZ6 P31274	Q96CA4 Q9GZZ0
PDB IDs		2LP0 2MSY
Enriched GO Terms of Interacting Partners?
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