HOXC9 and CBX6

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXC9	CBX6
Description		homeobox C9	chromobox 6
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome	Nucleus Nucleoplasm Chromosome PcG Protein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways			Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Body shape index ( 34021172) Heel bone mineral density ( 30598549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bladder cancer ( 24163127 20972438) Plateletcrit ( 32888494)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	3 interacting genes: HOXC9 PCGF2 PCGF6
Entrez ID		3225	23466
HPRD ID		00857	13005
Ensembl ID		ENSG00000180806	ENSG00000183741
Uniprot IDs		A0A024RAZ6 P31274	B0QXZ6 O95503
PDB IDs		2LP0 2MSY	3GV6 3I90
Enriched GO Terms of Interacting Partners?
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