HOXC8 and GSTO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HOXC8	GSTO2
Description		homeobox C8	glutathione S-transferase omega 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Microtubule Cytoskeleton	Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Identical Protein Binding Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Glutathione Metabolic Process Xenobiotic Metabolic Process L-ascorbic Acid Metabolic Process Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification
Pathways			Glutathione conjugation Vitamin C (ascorbate) metabolism
Drugs			Glutathione
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		107 interacting genes: ADAMTSL4 ANKS1A BLZF1 BMPR1A BTG2 C11orf1 C19orf54 C1orf109 CADPS CCM2 CEP70 CRYBA1 CYSRT1 DLX2 DLX5 DVL3 DZIP3 ECM1 FNTB GMNN GOLGA6L9 GSTO2 GYS1 HESX1 HOMEZ HOXD3 HSF2BP IKZF3 JUN KCTD9 KHDC1 KPRP KRT34 KRT35 KRT36 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-3 KRTAP19-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LDLRAP1 LDOC1 LHX2 LHX3 LRP2BP MAPK8IP2 MEOX1 MEOX2 METTL15 MGAT5B MSX1 NADSYN1 NBPF19 NFKBID NID2 NOTCH2NLA OIP5 PAX5 PAX6 PAX8 PBX1 PBX2 PBX4 PDE4DIP PFDN5 PLA2G10 PLEKHG4 POU2AF1 POU6F2 PPARA PRDM14 PRDM6 RBCK1 RBPMS SLAIN1 SMAD1 SMAD4 SMAD6 SNX17 TBC1D1 TBX19 TBX22 TEKT4 TLE5 TNS2 TRAF1 TRIB3 TRIM27 TRIM42 TRIP6 TSC1 USP54 VENTX WWOX ZFP90 ZMAT5 ZNF34 ZRANB1	11 interacting genes: CREBBP GCA HOXC8 INCA1 KLHL10 NTAQ1 PFDN5 POLR1C PWWP3A SMARCC1 TFAP2A
Entrez ID		3224	119391
HPRD ID		00856	13614
Ensembl ID		ENSG00000037965	ENSG00000065621
Uniprot IDs		P31273	Q9H4Y5
PDB IDs			3Q18 3Q19 3QAG
Enriched GO Terms of Interacting Partners?
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