HCFC1 and ASF1B

Number of citations of the paper that reports this interaction (PubMedID 20133788)
33

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HCFC1	ASF1B
Description		host cell factor C1	anti-silencing function 1B histone chaperone
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Membrane Axon Dendrite Protein-containing Complex Histone Methyltransferase Complex Neuronal Cell Body Set1C/COMPASS Complex MLL1 Complex	Chromatin Nucleoplasm Protein-containing Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Cadherin Binding DNA-binding Transcription Factor Binding	Protein Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription, DNA-templated Cell Cycle Positive Regulation Of Gene Expression Release From Viral Latency Regulation Of Protein-containing Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Cellular Response To Organic Cyclic Compound	Blastocyst Hatching DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Spermatogenesis Cell Differentiation
Pathways		Transcriptional activation of mitochondrial biogenesis HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338)
Interacting Genes		34 interacting genes: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 FOXK2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIAH1 SIN3A SP1 SUMO2 TAF9 THAP11 THAP7 YY1 ZBTB17	14 interacting genes: AKAP8L ASF1A CDIN1 CHAF1A CHAF1B H3-3A H3C3 H3C6 H4-16 H4C6 HCFC1 TAF1 TLK1 TLK2
Entrez ID		3054	55723
HPRD ID		02061	16460
Ensembl ID		ENSG00000172534	ENSG00000105011
Uniprot IDs		A6NEM2 P51610	A0A024R7G4 Q9NVP2
PDB IDs		4GO6 4N39 4N3A 4N3B 4N3C 5LWV 6MA1 6MA2 6MA3 6MA4 6MA5	5BNX 5BO0
Enriched GO Terms of Interacting Partners?
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