GTF2E2 and XPA

Number of citations of the paper that reports this interaction (PubMedID 7876263)
49

Data Source:
HPRD (in vitro)

		GTF2E2	XPA
Description		general transcription factor IIE subunit 2	XPA, DNA damage recognition and repair factor
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Nuclear Speck	Nucleotide-excision Repair Factor 1 Complex Nucleus Nucleoplasm Cytoplasm Intercellular Bridge
	Molecular Function	DNA Binding RNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Damaged DNA Binding Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter	Nucleotide-excision Repair, DNA Damage Recognition DNA Repair Base-excision Repair UV Protection Response To Auditory Stimulus Nucleotide-excision Repair, DNA Incision Protein Localization To Nucleus UV-damage Excision Repair Nucleotide-excision Repair Involved In Interstrand Cross-link Repair
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Dual incision in TC-NER
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Glaucoma (primary open-angle) ( 33627673) Mean corpuscular volume ( 32888494) Metabolite levels (X-11787) ( 23934736)	Hypothyroidism ( 27182965) Obesity-related traits ( 23251661) Serum thyroid-stimulating hormone levels ( 24852370) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		26 interacting genes: APP ATF7IP CCNH CDK7 ERCC3 ERCC6 EXOC8 FOS GTF2A1 GTF2B GTF2E1 GTF2F1 GTF2F2 GTF2H1 JUN KAT5 KLF5 MCC MDM2 MNAT1 NUP62 PICK1 SND1 SUPT16H TBP XPA	52 interacting genes: AP2M1 ARID3A ATM ATR AURKA BMPR1A BUB1 DDB1 DDB2 DLC1 DVL3 ERCC1 ERCC4 ERCC6 FBXW7 GPN1 GTF2E2 GTF2H1 HERC2 MEOX2 MLH1 MLH3 MSH2 MSH3 MUTYH NDEL1 NRAS PCNA PDGFRL PICK1 PMS2 POLR1C PRDM16 PRKDC PSMB1 RASSF1 RB1 RHOU RPA1 RPA2 RPA4 SKIL SMAD2 SNPH SRC STK11 TBC1D7 TRIM27 VPS26C XAB2 XPC ZNF655
Entrez ID		2961	7507
HPRD ID		01800	02045
Ensembl ID		ENSG00000197265	ENSG00000136936
Uniprot IDs		P29084	P23025
PDB IDs		1D8J 1D8K 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L	1D4U 1XPA 2JNW 6J44 6LAE 6RO4
Enriched GO Terms of Interacting Partners?
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