CXCL1 and CXCL6

Number of citations of the paper that reports this interaction (PubMedID 28381538)
37

Data Source:
BioGRID (pull down)

		CXCL1	CXCL6
Description		C-X-C motif chemokine ligand 1	C-X-C motif chemokine ligand 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Specific Granule Lumen Tertiary Granule Lumen	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Protein Binding Chemokine Activity Enzyme Activator Activity Growth Factor Activity CXCR Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Nervous System Development Negative Regulation Of Cell Population Proliferation Actin Cytoskeleton Organization Neutrophil Chemotaxis Intracellular Signal Transduction Regulation Of Catalytic Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Leukocyte Homeostasis Chemotaxis Inflammatory Response Signal Transduction Cell-cell Signaling Neutrophil Chemotaxis Regulation Of Chemokine Production Neutrophil Activation Defense Response To Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling Neutrophil degranulation	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Anxiety disorder ( 25390645) Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Growth-regulated protein alpha levels ( 27989323) Inflammatory bowel disease ( 23128233)	Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Eosinophil percentage of granulocytes ( 27863252) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		13 interacting genes: ACKR1 CCL11 CXCL5 CXCL6 CXCR1 CXCR2 ESR1 HIPK2 HRAS MEOX2 MMP9 PTEN XRCC3	14 interacting genes: CCL11 CCL5 CCL7 CCL8 CXCL1 CXCL10 CXCL12 CXCL2 CXCL3 CXCR1 CXCR2 MMP9 PF4 PPBP
Entrez ID		2919	6372
HPRD ID		01119	00735
Ensembl ID		ENSG00000163739	ENSG00000124875
Uniprot IDs		P09341	P80162
PDB IDs		1MGS 1MSG 1MSH 1ROD
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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