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CXCL1

Description C-X-C motif chemokine ligand 1
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Specific Granule Lumen
  • Tertiary Granule Lumen
Molecular Function
  • Signaling Receptor Binding
  • Protein Binding
  • Chemokine Activity
  • Enzyme Activator Activity
  • Growth Factor Activity
  • CXCR Chemokine Receptor Binding
Biological Process
  • Chemotaxis
  • Inflammatory Response
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Nervous System Development
  • Negative Regulation Of Cell Population Proliferation
  • Actin Cytoskeleton Organization
  • Neutrophil Chemotaxis
  • Intracellular Signal Transduction
  • Regulation Of Catalytic Activity
  • Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
  • Chemokine-mediated Signaling Pathway
  • Cellular Response To Lipopolysaccharide
Pathways
  • Chemokine receptors bind chemokines
  • G alpha (i) signalling events
  • Interleukin-10 signaling
  • Neutrophil degranulation
Drugs
Diseases
GWAS
  • Anxiety disorder ( 25390645)
  • Blood protein levels ( 30072576 29875488 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Growth-regulated protein alpha levels ( 27989323)
  • Inflammatory bowel disease ( 23128233)
Interacting Genes 13 interacting genes: ACKR1 CCL11 CXCL5 CXCL6 CXCR1 CXCR2 ESR1 HIPK2 HRAS MEOX2 MMP9 PTEN XRCC3
Entrez ID 2919
HPRD ID 01119
Ensembl ID ENSG00000163739
Uniprot IDs P09341
PDB IDs 1MGS 1MSG 1MSH 1ROD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025