DCPS and CSNK2A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		DCPS	CSNK2A2
Description		decapping enzyme, scavenger	casein kinase 2 alpha 2
Image
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Chromatin Acrosomal Vesicle Nucleus Nucleoplasm Cytosol Plasma Membrane Protein Kinase CK2 Complex
	Molecular Function	RNA 7-methylguanosine Cap Binding Exoribonuclease Activity Protein Binding Identical Protein Binding M7G(5')pppN Diphosphatase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein N-terminus Binding Protein Serine Kinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Cellular Response To Menadione Negative Regulation Of Programmed Cell Death Exonucleolytic Catabolism Of Deadenylated MRNA MRNA Cis Splicing, Via Spliceosome RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Apoptotic Process Cell Cycle Spermatogenesis Wnt Signaling Pathway Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Cerebral Cortex Development Regulation Of Cell Cycle Liver Regeneration Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of Chromosome Separation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways		mRNA decay by 3' to 5' exoribonuclease	Synthesis of PC WNT mediated activation of DVL Condensation of Prometaphase Chromosomes Signal transduction by L1 Regulation of TP53 Activity through Phosphorylation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding ROS sensing by NFE2L2 Receptor Mediated Mitophagy RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN stability and activity
Drugs		7-methyl-GpppA 7-methyl-7,8-dihydroguanosine-5'-diphosphate 7-methyl-5'-guanylic acid 7-methyl-guanosine-5'-triphosphate-5'-guanosine 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine	[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid Fostamatinib
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252)	Primary biliary cholangitis ( 28425483) Rosacea symptom severity ( 29771307) Systemic lupus erythematosus ( 28714469) Telomere length ( 24795349)
Interacting Genes		10 interacting genes: CDC20 CDC27 CHST4 CSNK2A2 FZR1 GPC5 KPNA2 KPNA5 KPNA6 YWHAQ	107 interacting genes: ABCA1 ACACA ADH1A AMFR AQP4 ARRB2 ASL ATF1 ATF2 ATG16L1 BHLHE41 BID CABP1 CALM1 CASQ2 CAV1 CDC37 CLTB CREBBP CREM CSN3 CSNK2B CTDP1 DCPS DELEC1 EEF1B2 EIF2B2 EIF2B5 EIF4EBP1 ERCC6 ERH FGF1 FGF2 FKBP3 FOS GOT2 GRIN2A GRIN2B GTF2A1 GTF2A1L H1-2 HDAC1 HDAC2 HDAC6 HMGA1 HMGA2 HNRNPC HSP90AA1 HSP90B1 HSPH1 IL16 KDM1A KIF1C KLF1 LAMC3 LGALS3 MAF1 MAPK14 MDM2 MGMT MS4A1 MYC MYCN MYF5 NAP1L4 NCL NR1D2 P4HB PAK1 PICK1 PIN1 PIN4 PPP1R1B PPP1R2 PPP1R8 PRNP PTEN PTPN1 PTPRC RAD1 RAD9A RELA RGS19 SAT1 SLC18A2 SMURF1 SNCA SNX6 SPIB SPP1 STX1A TCF7L2 TCOF1 TGFBR1 TGM2 TOP1 TP53 TP63 TRIM41 TTLL12 UBE2R2 WAS XRCC1 ZNF219 ZNF423 ZNF670 ZNHIT3
Entrez ID		28960	1459
HPRD ID		16787	00279
Ensembl ID		ENSG00000110063	ENSG00000070770
Uniprot IDs		A0A384MTI8 Q96C86	H3BNI9 P19784
PDB IDs		1ST0 1ST4 1XML 1XMM 3BL7 3BL9 3BLA 4QDE 4QDV 4QEB 5OSY	3E3B 3OFM 3U87 5M4U 5M56 5OOI 5Y9M 5YF9 5YWM 6HMB 6HMC 6HMD 6HMQ 6L20 6QY8 6QY9 6TE2 6TEW 6TGU 7A1B 7A1Z 7A22 7A2H
Enriched GO Terms of Interacting Partners?
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