Description |
Rap guanine nucleotide exchange factor 1 |
RAP1B, member of RAS oncogene family |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Cerebrospinal fluid α-synuclein levels ( 29959729)
- Cutaneous malignant melanoma ( 32341527)
- Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
- Kidney volume ( 34128465)
- Nevus count or cutaneous melanoma ( 32341527)
- Optic disc size ( 31809533)
|
- Femoral neck bone mineral density ( 32239398)
- Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398)
- HDL cholesterol levels in HIV infection ( 33109212)
- White blood cell count ( 20139978)
|
Interacting Genes |
20 interacting genes:
ABL1
ATXN1
BCAR1
CRK
CRKL
EGFR
GRB2
HCK
HRAS
MBIP
NEDD9
PDGFRA
RAP1A
RAP1B
RAP2B
RHOQ
RPS15
RRAS2
SHC1
SLC20A1
|
30 interacting genes:
A2M
ALAS1
APLP1
APP
CCT7
CHGB
CSAD
DDAH2
FAF1
HRAS
KMT2B
LRIF1
MTUS2
PDHB
PKM
PRKACA
RAB7B
RALGDS
RAPGEF1
RASSF5
RGL2
RGS2
RPTOR
SDF4
SMURF2
TLE1
TP53
UNC119
ZDHHC17
ZNF135
|
Entrez ID |
2889 |
5908 |
HPRD ID |
02627 |
01546 |
Ensembl ID |
ENSG00000107263
|
ENSG00000127314
|
Uniprot IDs |
Q13905
|
A0A024RB87
B7ZAY2
P61224
|
PDB IDs |
5L23
|
3BRW
3CF6
4DXA
4HDO
4HDQ
4M8N
4MGI
4MGK
4MGY
4MGZ
4MH0
5KHO
6AXF
6BA6
6KYK
6OQ3
6OQ4
6UZK
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|