POLL and TNFRSF10D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		POLL	TNFRSF10D
Description		DNA polymerase lambda	TNF receptor superfamily member 10d
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Site Of Double-strand Break	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Replication Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process	Apoptotic Process Signal Transduction Negative Regulation Of Apoptotic Process
Pathways		Nonhomologous End-Joining (NHEJ)	Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 20732625) Lymphocyte percentage of white cells ( 32888494)
Interacting Genes		40 interacting genes: APP CCNDBP1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1	28 interacting genes: APOL3 ARFIP1 CIAO2A ECPAS FAM114A1 GAD2 HSBP1L1 INPP5K LAT MIEF1 MTERF4 PCYT1A PITPNC1 PLPP6 POLL RBP1 RMDN2 SEMA4G SENP2 SLC39A7 SUCLA2 TARS2 TBRG4 THAP4 TNFRSF10A TNFRSF10B TNFSF10 TUFM
Entrez ID		27343	8793
HPRD ID		09394	04682
Ensembl ID		ENSG00000166169	ENSG00000173530
Uniprot IDs		A8K860 B4DE17 Q9UGP5	Q9UBN6
PDB IDs		1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G
Enriched GO Terms of Interacting Partners?
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