POLL and ZRANB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		POLL	ZRANB1
Description		DNA polymerase lambda	zinc finger RANBP2-type containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Site Of Double-strand Break	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity	Thiol-dependent Deubiquitinase Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Replication Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process	Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination
Pathways		Nonhomologous End-Joining (NHEJ)	Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340) Lung cancer ( 34062886)
Interacting Genes		40 interacting genes: APP CCNDBP1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1	153 interacting genes: AKT1 ANKRD11 AP1M1 ARHGEF5 ARRDC2 ARRDC3 BAHD1 BRD1 BYSL C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCNL1 CDC45 CDC5L CDK18 CDKL3 CNNM3 CORO7 CPNE7 CSNK1A1 CWF19L2 DCX DDX6 DNAJB13 DTNB DUSP13 EHHADH EIF3D ENKD1 ERF FAIM FAM124B FAM161A FAM161B FAM214B FAM50B FARS2 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GPKOW HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METAP1 METTL21A MFAP1 MID2 MPPED1 MYEF2 NEK6 NUDT16L1 NUDT21 PBLD PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL POLR1C PPP1R18 PRPF18 PRPF3 PRPF31 PSPC1 QARS1 RAPGEF3 RASAL3 RHOBTB3 RNPS1 SDCBP SNCA STAMBPL1 STK19 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEA2 TCEANC THAP7 TIE1 TLE5 TNS4 TOLLIP TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TWIST1 UBASH3A UBC UBE2S USP2 UVRAG VAV3 VEZF1 WT1 XRCC5 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF581 ZNF587 ZNF599 ZNF629 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837
Entrez ID		27343	54764
HPRD ID		09394	11738
Ensembl ID		ENSG00000166169	ENSG00000019995
Uniprot IDs		A8K860 B4DE17 Q9UGP5	Q9UGI0
PDB IDs		1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G	3ZRH 5AF6
Enriched GO Terms of Interacting Partners?
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