UBE2S and LINC00839

Number of citations of the paper that reports this interaction (PubMedID 30631154)
13

Data Source:
BioGRID (unspecified method)

		UBE2S	LINC00839
Description		ubiquitin conjugating enzyme E2 S	long intergenic non-protein coding RNA 839
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Anaphase-promoting Complex Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Anaphase-promoting Complex Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Exit From Mitosis Free Ubiquitin Chain Polymerization Anaphase-promoting Complex-dependent Catabolic Process Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Cell Division Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase APC/C:Cdc20 mediated degradation of mitotic proteins Phosphorylation of the APC/C APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Senescence-Associated Secretory Phenotype (SASP) CDK-mediated phosphorylation and removal of Cdc6 Transcriptional Regulation by VENTX Synthesis of active ubiquitin: roles of E1 and E2 enzymes Aberrant regulation of mitotic exit in cancer due to RB1 defects Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		34 interacting genes: AKT1 ANAPC1 ANAPC11 ANAPC4 ANAPC5 ANAPC7 APP ATXN3 BIRC2 CDC16 CDC20 CDC23 CDC27 CTNNB1 CYLD HERC1 LINC00839 MDM2 OTUB1 OTUD7B PRKN RBCK1 STAMBP UBA1 UBA6 UBB UBC UCHL3 USP2 USP21 USP5 USP7 VHL ZRANB1	82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC168 CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1
Entrez ID		27338	84856
HPRD ID		15603	17516
Ensembl ID		ENSG00000108106	ENSG00000185904
Uniprot IDs		Q16763
PDB IDs		1ZDN 5BNB 5L9T 6QH3 6QHK 6S96 6S98
Enriched GO Terms of Interacting Partners?
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