TRPC4AP and CHMP4C

Number of citations of the paper that reports this interaction (PubMedID 16730941)
66

Data Source:
HPRD (two hybrid)

		TRPC4AP	CHMP4C
Description		transient receptor potential cation channel subfamily C member 4 associated protein	charged multivesicular body protein 4C
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Calcium Channel Activity Protein Binding Phosphatase Binding Ubiquitin Ligase-substrate Adaptor Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Macroautophagy Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly
Pathways		TRP channels	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Basal cell carcinoma ( 33549134) Blood protein levels ( 28240269) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		18 interacting genes: CHMP4C CHUK CPNE1 CUL4B EDEM2 IKBKB IKBKG MED26 MTDH PCDH11X PGLYRP4 RIPK1 TAB1 TNFRSF1A TRADD TRAF2 UQCC1 VMP1	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		26133	92421
HPRD ID		09238	18135
Ensembl ID		ENSG00000100991	ENSG00000164695
Uniprot IDs		B4DW48 Q8TEL6	Q96CF2
PDB IDs			3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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