PPP1R16B and FAM83A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPP1R16B	FAM83A
Description		protein phosphatase 1 regulatory subunit 16B	family with sequence similarity 83 member A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)	Urinary uromodulin levels ( 24578125)
Interacting Genes		45 interacting genes: ATPAF2 CDCA7L CDK5RAP1 CEP55 CEP70 CRX DVL2 DVL3 FAM83A FAM83D FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MCEE MISP MYL9 NEFL NFX1 PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 SSR4 TACO1 TADA2A TASOR2 TFIP11 TLE5 TTI1 TUFM TXN2 ZNF410 ZNF564	23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A
Entrez ID		26051	84985
HPRD ID		15168	17489
Ensembl ID		ENSG00000101445	ENSG00000147689
Uniprot IDs		Q96T49	Q86UY5
PDB IDs			4URJ
Enriched GO Terms of Interacting Partners?
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