PPP1R16B and FLYWCH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPP1R16B	FLYWCH1
Description		protein phosphatase 1 regulatory subunit 16B	FLYWCH-type zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		45 interacting genes: ATPAF2 CDCA7L CDK5RAP1 CEP55 CEP70 CRX DVL2 DVL3 FAM83A FAM83D FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MCEE MISP MYL9 NEFL NFX1 PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 SSR4 TACO1 TADA2A TASOR2 TFIP11 TLE5 TTI1 TUFM TXN2 ZNF410 ZNF564	14 interacting genes: CCDC125 CCDC136 ERBB3 GMCL1 GOLGA6L9 HOOK2 HSF2BP KIFC3 LHX2 MTUS2 PICK1 PPP1R16B SETDB1 TRAF2
Entrez ID		26051	84256
HPRD ID		15168	13222
Ensembl ID		ENSG00000101445	ENSG00000059122
Uniprot IDs		Q96T49	Q4VC44
PDB IDs			2RPR
Enriched GO Terms of Interacting Partners?
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