ZNF473 and CLK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ZNF473	CLK2
Description		zinc finger protein 473	CDC like kinase 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cajal Body	Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II MRNA 3'-end Processing By Stem-loop Binding And Cleavage Positive Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation
Pathways		SLBP independent Processing of Histone Pre-mRNAs Generic Transcription Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs			Fostamatinib
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: AEN CLK2 CLK3 DHX57 GPATCH2L KRTAP10-10 KRTAP10-8 KRTAP10-9 LSM11 NUP62 PRPF31 RBM10 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF408 ZNF497 ZNF792 ZNF837 ZSCAN12	53 interacting genes: AKT1 ASPSCR1 CACTIN CLASRP CLK1 CLK3 CPSF7 DDIT4L ECE1 EHHADH GMCL1 GTPBP2 KLHL2 LNX1 LUZP4 MRPL4 NXF1 PRM1 PRPF38A PTPN1 RBM39 RNF8 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 SRSF3 TACC2 TRIM27 TRIM50 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF136 ZNF263 ZNF317 ZNF394 ZNF398 ZNF436 ZNF440 ZNF473 ZNF491 ZNF558 ZNF764 ZNF768 ZNF837 ZRSR2 ZSCAN21
Entrez ID		25888	1196
HPRD ID		11721	04289
Ensembl ID		ENSG00000142528	ENSG00000176444
Uniprot IDs		A0A024QZI1 B4DY71 F8WEC7 Q8WTR7	A8K7I0 B7Z8N6 P49760
PDB IDs		2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5	3NR9 5UNP 6FYI 6FYK 6FYL 6KHE
Enriched GO Terms of Interacting Partners?
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