CLK2 and LUZP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLK2	LUZP4
Description		CDC like kinase 2	leucine zipper protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity	RNA Binding Protein Binding
	Biological Process	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation	MRNA Transport
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Fostamatinib
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		53 interacting genes: AKT1 ASPSCR1 CACTIN CLASRP CLK1 CLK3 CPSF7 DDIT4L ECE1 EHHADH GMCL1 GTPBP2 KLHL2 LNX1 LUZP4 MRPL4 NXF1 PRM1 PRPF38A PTPN1 RBM39 RNF8 RNPS1 RSRP1 SDCBP SNIP1 SNRNP70 SRPK2 SRRM1 SRSF3 TACC2 TRIM27 TRIM50 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF136 ZNF263 ZNF317 ZNF394 ZNF398 ZNF436 ZNF440 ZNF473 ZNF491 ZNF558 ZNF764 ZNF768 ZNF837 ZRSR2 ZSCAN21	22 interacting genes: APPBP2 BACH2 CCDC6 CLK2 DDX39B DVL3 EMD FOS FOSL2 HSF2BP KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 LNX1 MORF4L2 NXF1 RCOR3 SRPK2 SRRM4 TLK1 TNS2
Entrez ID		1196	51213
HPRD ID		04289	06589
Ensembl ID		ENSG00000176444	ENSG00000102021
Uniprot IDs		A8K7I0 B7Z8N6 P49760	Q9P127
PDB IDs		3NR9 5UNP 6FYI 6FYK 6FYL 6KHE
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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