GABARAPL1 and TBC1D5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid, pull down)

		GABARAPL1	TBC1D5
Description		GABA type A receptor associated protein like 1	TBC1 domain family member 5
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GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Autophagosome Golgi Apparatus Cytosol Endosome Membrane Retromer Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	GTPase Activator Activity Protein Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Aspartate aminotransferase levels ( 33547301) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 32888494 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Parkinson's disease ( 32201043) Platelet count ( 32888494 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 32888494 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		74 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4B ATG4D BNIP3L BSCL2 BSDC1 CALCOCO1 CALCOCO2 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 HSP90AA1 HSP90AB1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV MLX NEDD4 NFIA OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM32 ULK1 UMAD1 VDR WDFY3 ZBTB22	10 interacting genes: AP2M1 ATXN1 CHIA EIF1AD FBXL7 GABARAPL1 GABARAPL2 MAP1LC3A UBC ZBTB25
Entrez ID		23710	9779
HPRD ID		07601	10262
Ensembl ID		ENSG00000139112	ENSG00000131374
Uniprot IDs		A0A024RAP5 Q9H0R8	B9A6K1 Q92609
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL	5GTU
Enriched GO Terms of Interacting Partners?
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