GABARAPL1 and TBC1D25

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid, pull down)

		GABARAPL1	TBC1D25
Description		GABA type A receptor associated protein like 1	TBC1 domain family member 25
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Autophagosome Cytoplasmic Vesicle
	Molecular Function	Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	GTPase Activator Activity Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation
Pathways		Macroautophagy	TBC/RABGAPs
Drugs
Diseases
GWAS
Interacting Genes		74 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4B ATG4D BNIP3L BSCL2 BSDC1 CALCOCO1 CALCOCO2 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 HSP90AA1 HSP90AB1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV MLX NEDD4 NFIA OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM32 ULK1 UMAD1 VDR WDFY3 ZBTB22	17 interacting genes: DDX3X FAM9B FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 KCNIP1 LARP1B LGALS14 LMNTD2 MAP1LC3A MAP1LC3B MAP1LC3C RAB2A RUSC1 TRIML2
Entrez ID		23710	4943
HPRD ID		07601	08948
Ensembl ID		ENSG00000139112	ENSG00000068354
Uniprot IDs		A0A024RAP5 Q9H0R8	B4DF03 Q3MII6
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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