TRIM29 and VIM

Number of citations of the paper that reports this interaction (PubMedID 7644499)
12

Data Source:
HPRD (two hybrid, in vitro)

		TRIM29	VIM
Description		tripartite motif containing 29	vimentin
Image
GO Annotations	Cellular Component	Lysosome Adherens Junction	Cytoplasm Peroxisome Microtubule Organizing Center Cytosol Polysome Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Nuclear Matrix Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Phagocytic Vesicle Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein Domain Specific Binding Identical Protein Binding Scaffold Protein Binding Keratin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Negative Regulation Of Neuron Projection Development Astrocyte Development Positive Regulation Of Collagen Biosynthetic Process Regulation Of MRNA Stability Intermediate Filament Organization Positive Regulation Of Translation Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Cellular Response To Interferon-gamma
Pathways		Interferon gamma signaling	Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling RHOBTB1 GTPase cycle Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy
Drugs			Artenimol Phenethyl Isothiocyanate
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)	Aspartate aminotransferase levels ( 33547301) Cholesterol, total ( 24097068) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)
Interacting Genes		56 interacting genes: ACTN3 ANKS1A ATM ATP1A3 CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 HNRNPLL IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	175 interacting genes: ABLIM1 AKT1 ANKRD35 ANXA7 APIP APLP1 APP ARMC7 ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 BYSL C2CD6 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CBX8 CCDC187 CDH5 CDK1 CDKN1A CEP126 CHD3 COPS6 CRCT1 CREB1 CRMP1 CT55 CWF19L2 DCTN1 DEFB1 DES DIS3L2 DNM1L DPPA4 DSP DUX4 DYNLL1 ENTR1 ESS2 FABP4 FAM107A FAM118B FAM161A FUBP1 FXR1 FXR2 GADD45A GEM GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HSPB1 HTRA2 ING5 IP6K1 ITGB4 IVNS1ABP KARS1 KAT7 KIAA0408 KIF15 KIF9 KIFC3 KRT20 KRT75 LGALS14 LINC01554 LORICRIN LRIF1 MAFG MAN2A2 MCPH1 MEN1 MICAL1 MRPL44 MTDH NEFL NEFM NFATC2 NFKBID NIF3L1 NME2 NOC4L NR1H2 NUP85 OGT OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PPP1R18 PRKACA PRPH PSMA1 PSMC5 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SCNM1 SERBP1 SETDB1 SH3GL3 SH3YL1 SHANK3 SIRPA SIRT6 SLC25A6 SLC27A6 SMAD3 SMARCB1 SRRT STK19 STX1A SUMO2 SUMO3 SYN1 TAB2 TCEA2 TCHP TLE5 TNFRSF14 TNNT1 TRIM14 TRIM15 TRIM28 TRIM29 TRIOBP TSC1 TSC22D1 TTR TUBA1C TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1 YWHAE YWHAZ ZHX1 ZNF384 ZNF572
Entrez ID		23650	7431
HPRD ID		10280	01899
Ensembl ID		ENSG00000137699	ENSG00000026025
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	P08670 V9HWE1
PDB IDs		2CSV	1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1 4MCY 4MCZ 4MD0 4MD5 4MDI 4MDJ 4YPC 4YV3 5WHF 6ATF 6ATI 6BIR
Enriched GO Terms of Interacting Partners?
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