MKRN1 and NAA10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MKRN1	NAA10
Description		makorin ring finger protein 1	N-alpha-acetyltransferase 10, NatA catalytic subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	DNA Packaging Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
Pathways		AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)	Systemic lupus erythematosus ( 26502338)
Interacting Genes		26 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 PABPC1 RAD23A RAD23B RPS10 SDCBP SLC13A1 TSC2 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1	55 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CDCA5 CEP44 CREB3 CREBRF DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L HIF1A HIF1AN HSPA4 KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655
Entrez ID		23608	8260
HPRD ID		09673	02056
Ensembl ID		ENSG00000133606	ENSG00000102030
Uniprot IDs		Q9UHC7	B7Z9N2 P41227
PDB IDs			6C95 6C9M 6PPL 6PW9
Enriched GO Terms of Interacting Partners?
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