MKRN1 and MTURN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MKRN1	MTURN
Description		makorin ring finger protein 1	maturin, neural progenitor differentiation regulator homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Cytoplasm
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)	Cadmium levels ( 26025379)
Interacting Genes		26 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 PABPC1 RAD23A RAD23B RPS10 SDCBP SLC13A1 TSC2 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1	23 interacting genes: AP2M1 APP ARRDC1 DAZAP2 MKRN1 PLEKHB2 REL RNF41 RPS27A SH3RF1 SSX1 SUSD6 TMEM239 TNFRSF19 TP53BP2 TRAF6 TRIM38 TRIM39 TRIM5 TRIM8 UBA52 UBB UBC
Entrez ID		23608	222166
HPRD ID		09673	07635
Ensembl ID		ENSG00000133606	ENSG00000180354
Uniprot IDs		Q9UHC7	Q8N3F0
PDB IDs
Enriched GO Terms of Interacting Partners?
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