QPRT and BCKDK

		QPRT	BCKDK
Description		quinolinate phosphoribosyltransferase	branched chain keto acid dehydrogenase kinase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome Catalytic Complex	Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
	Molecular Function	Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity Protein Binding Identical Protein Binding	Protein Serine/threonine Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
	Biological Process	NAD Biosynthetic Process NAD Metabolic Process Quinolinate Catabolic Process	Protein Phosphorylation Isoleucine Catabolic Process Leucine Catabolic Process Valine Catabolic Process Spermatogenesis Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Regulation Of Glucose Metabolic Process Phosphorylation Negative Regulation Of Cellular Amino Acid Metabolic Process
Pathways		Nicotinate metabolism	Branched-chain amino acid catabolism
Drugs		Niacin	Adenosine 5'-[gamma-thio]triphosphate
Diseases
GWAS			Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Parkinson's disease ( 25064009) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498)
Interacting Genes		11 interacting genes: ADAMTSL4 BCKDK ETS1 GIT2 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-8 KRTAP4-12 NOTCH2NLA SUFU	20 interacting genes: APP BCKDHB CDIPT EIF3C EPS8 FBXO7 FOXO1 FXR1 FXR2 GUCA1A LSM8 NR5A2 PCDHB9 QPRT SETD1A SPTA1 STAT3 TAOK2 TRAF4 ZNF267
Entrez ID		23475	10295
HPRD ID		06950	12523
Ensembl ID		ENSG00000103485	ENSG00000103507
Uniprot IDs		B4DDH4 Q15274 V9HWJ5	A0A024QZA9 O14874
PDB IDs		2JBM 4KWV 4KWW 5AYX 5AYY 5AYZ
Enriched GO Terms of Interacting Partners?
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