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BCKDK

Description branched chain keto acid dehydrogenase kinase
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
  • Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity
  • Protein Binding
  • ATP Binding
  • Kinase Activity
  • [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
Biological Process
  • Protein Phosphorylation
  • Isoleucine Catabolic Process
  • Leucine Catabolic Process
  • Valine Catabolic Process
  • Spermatogenesis
  • Cellular Amino Acid Catabolic Process
  • Branched-chain Amino Acid Catabolic Process
  • Regulation Of Glucose Metabolic Process
  • Phosphorylation
  • Negative Regulation Of Cellular Amino Acid Metabolic Process
Pathways
  • Branched-chain amino acid catabolism
Drugs
  • Adenosine 5'-[gamma-thio]triphosphate
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Parkinson's disease ( 25064009)
  • Systolic blood pressure ( 31928498)
  • Triglyceride levels ( 31928498)
  • Waist circumference ( 31928498)
Interacting Genes 20 interacting genes: APP BCKDHB CDIPT EIF3C EPS8 FBXO7 FOXO1 FXR1 FXR2 GUCA1A LSM8 NR5A2 PCDHB9 QPRT SETD1A SPTA1 STAT3 TAOK2 TRAF4 ZNF267
Entrez ID 10295
HPRD ID 12523
Ensembl ID ENSG00000103507
Uniprot IDs A0A024QZA9 O14874
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025