OTP and PDE6D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OTP	PDE6D
Description		orthopedia homeobox	phosphodiesterase 6D
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleoplasm Nuclear Body	Cytoplasm Cytosol Cytoskeleton Cilium Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	GTPase Inhibitor Activity Protein Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuroblast Proliferation Forebrain Neuron Differentiation Hypothalamus Cell Differentiation Neurohypophysis Development Neuron Differentiation	Visual Perception Negative Regulation Of Catalytic Activity Response To Stimulus
Pathways			ARL13B-mediated ciliary trafficking of INPP5E RAS processing
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149)	Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Interacting Genes		8 interacting genes: BEX1 CCL21 CDK6 CPNE7 EOMES PDE6D SLC12A7 TPGS2	25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR
Entrez ID		23440	5147
HPRD ID		05166	04056
Ensembl ID		ENSG00000171540	ENSG00000156973
Uniprot IDs		Q5XKR4	B8ZZK5 O43924 Q6IB24
PDB IDs			1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW
Enriched GO Terms of Interacting Partners?
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