NOMO1 and UPF2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		NOMO1	UPF2
Description		NODAL modulator 1	UPF2 regulator of nonsense mediated mRNA decay
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus Cytoplasm Cytosol Polysome Exon-exon Junction Complex Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Carbohydrate Binding Ribosome Binding	RNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Biological_process Negative Regulation Of Nodal Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Animal Organ Regeneration
Pathways			Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Theophylline
Diseases
GWAS			Diverticular disease ( 30177863)
Interacting Genes		24 interacting genes: ATF7IP BAG6 BAIAP3 CASP4 CFB DLG4 ECT2 EXOSC10 KCNA1 MPV17L NCLN NDE1 NTAN1 PDZD3 PPIE SHBG STAT1 TOM1L1 TRIM55 TRIM63 UBQLN4 UPF2 VWF ZNF75A	78 interacting genes: ABCF2 AGPAT1 AKTIP ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GATA3 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MTREX MYB NDUFA7 NOB1 NOMO1 NOP53 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SMG1 SSBP2 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID		23420	26019
HPRD ID		11398	10405
Ensembl ID		ENSG00000103512	ENSG00000151461
Uniprot IDs		Q15155	Q9HAU5
PDB IDs			1UW4 2WJV 4CEK 4CEM
Enriched GO Terms of Interacting Partners?
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