TBC1D1 and CWF19L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBC1D1	CWF19L2
Description		TBC1 domain family member 1	CWF19 like cell cycle control factor 2
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GO Annotations	Cellular Component	Nucleus	Post-mRNA Release Spliceosomal Complex
	Molecular Function	GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Protein Localization Activation Of GTPase Activity Regulation Of Cilium Assembly	MRNA Splicing, Via Spliceosome
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728) Bipolar disorder ( 34099189) Crohn's disease ( 23850713 23266558) Diastolic blood pressure ( 27841878 27618452) Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) High-sensitivity cardiac troponin T levels ( 33321125) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Periodontal microbiota ( 22699663) Pulse pressure ( 27841878) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Systolic blood pressure ( 27841878 27618452) Verbal declarative memory ( 25648963) Weight ( 28552196) White blood cell count ( 32888494)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Parkinson's disease progression (cognitive) ( 33111402) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		31 interacting genes: CALM1 CALM2 CALM3 CCDC185 CWF19L2 EFHC2 FAM161A FAM50B GABARAPL1 GMCL1 HOXC8 HSF2BP HSPB1 KRT75 L3MBTL3 LHX8 LNX1 LZTS1 MAP1LC3A MCRS1 PNKP RIN1 SMAD2 SYTL4 TCEA2 TNNC2 TSGA10IP TXLNA VPS52 YWHAG ZFP1	80 interacting genes: ABLIM3 APP AXIN2 BACH2 BRCA1 CALCOCO1 CALCOCO2 CARD10 CARD9 CCDC102B CCDC136 CCDC57 CCDC88B CEP63 CEP70 CEP76 CFAP53 CNTROB CWF19L1 DES DISC1 EXOC8 FAM9B FCHO1 FSD2 FXR1 FXR2 GAS8 GFAP GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOOK1 HOOK2 HSF2BP IKBKG IKZF1 KANK2 KASH5 KIF24 KIFC3 KRT40 LHX3 LHX9 LIMS1 LMNA LZTS1 LZTS2 M1AP MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 PDE4DIP PIBF1 PICK1 PSTPIP1 RINT1 SF3B4 SNW1 STX11 TAX1BP1 TBC1D1 TFIP11 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM37 TRIM54 TRIM9 VIM VPS52 ZBTB8A ZMYND12 ZNF35 ZNF655 ZRANB1
Entrez ID		23216	143884
HPRD ID		18161	13102
Ensembl ID		ENSG00000065882	ENSG00000152404
Uniprot IDs		B9A6J6 Q6PJJ8 Q86TI0 Q8NC59	Q2TBE0
PDB IDs		3QYE	6ID0 6ID1
Enriched GO Terms of Interacting Partners?
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